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Anti-ALOX5AP (Center) Antibody
Catalog #: 102-17687
Rabbit Anti-Human ALOX5AP (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P20292 |
| Gene Id | 241 |
| Gene Symbols | ALOX5AP |
| Protein Name / Synonyms | ALOX5AP (Center) |
| Clonality | Polyclonal |
| Preparation | This ALOX5AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from the Central region of human ALOX5AP. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Pig, Monkey, Rabbit
Other Names
ALOX5AP; FLAP; Arachidonate 5-lipoxygenase-activating protein; MK-886-binding protein
NCBI Accession #
NP_001191335.1;NP_001620.2
Other Accession #
P20291; P30357; P30356; P30355; Q2PG08; Q148F2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
18157
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-ALOX5AP Antibody (Center) (Cat# 102-17687) in K562 cell line lysates (35ug/lane). ALOX5AP(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.