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Anti-Alpha-1-Antichymotrypsin / AACT / SERPINA3 Antibody
Catalog #: 188-11003
Mouse anti-Human Alpha-1-Antichymotrypsin Antibody / AACT / SERPINA3
Product Description
Specifications
| Size | 20 µg, 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P01011 |
| Gene Id | 12 |
| Gene Symbols | SERPINA3,AACT,GIG24,GIG25 |
| Protein Name / Synonyms | Alpha-1-antichymotrypsin (ACT) (Cell growth-inhibiting gene 24/25 protein) (Serpin A3) [Cleaved into: Alpha-1-antichymotrypsin His-Pro-less] |
| Immunogen | A human partial recombinant protein was used as the immunogen for this Alpha-1-Antichymotrypsin antibody. |
| Isotype | IgG1 |
| Purity | Protein G affinity |
| Concentration (lot specific) | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Western blot: 0.5-1ug/ml IHC (Paraffin): 0.5-1ug/ml IF: 0.5-1ug/ml FACS:0.5-1ug/10e6 cells in 0.1ml |
| Domain / Region / Terminus | Cytoplasmic |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Alpha 1-Antichymotrypsin, also called AACT and SERPINA3, inhibits the activity of certain proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes. This protein is produced in the liver, and is an acute phase protein that is induced during inflammation. [Wiki]
Storage
Store the Alpha-1-Antichymotrypsin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.