RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-ALPP (N-term) Antibody

Catalog #: 102-10251

Mouse Anti-Human ALPP (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Accession Number
P05187
Gene Id
250
Gene Symbols
ALPP
Protein Name / Synonyms
ALPP (N-term)
ClonalityMonoclonal
PreparationThis ALPP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human ALPP.
Concentration (lot specific)
0.420 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Specificity

Other Names
ALPP; PLAP; Alkaline phosphatase, placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1
NCBI Accession #
NP_001623.3
Other Accession #
P10696; NP_001623.3

Format

Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
57954
Recommended Dilutions
WB: 1:100-500
ALPP Antibody (N-term) (Cat# 102-10251) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the ALPP antibody detected the ALPP protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.