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Anti-AMACR / p504S Antibody (Prostate Cancer Marker), Sodium Azide Free
Catalog #: 188-11012-SAF
Mouse anti-Human AMACR / p504S Antibody (Prostate Cancer Marker) [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | Q9UHK6 |
| Gene Id | 23600 |
| Gene Symbols | AMACR |
| Protein Name / Synonyms | Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase) |
| Immunogen | A recombinant human protein was used as the immunogen for the AMACR antibody. |
| Isotype | IgG |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in sterile PBS, BSA free, sodium azide free |
| Recommended Applications | Immunohistology (FFPE): 1-2ug/ml for 30 minutes at RT IF: 1-2ug/ml |
| Domain / Region / Terminus | Cytoplasmic |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
Storage
Store the AMACR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.