Anti-AMPK gamma (PRKAG1) (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P54619\|Q09138\|O54950\|P58108\|NP_997626
Gene Id	5571
Gene Symbols	PRKAG1
Protein Name / Synonyms	5'-AMP-activated protein kinase subunit gamma-1, AMPK gamma1, AMPK subunit gamma-1, AMPKg, PRKAG1
Clonality	Polyclonal
Clone	RB3173
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, IHC-P
Research Area	AMPK Signaling, Energy Metabolism
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

PRKAG1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK.

Other Information

NCBI Accession #

NP_001193638.1;NP_001193639.1;NP_002724.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Calculated Molecular Weight (Da)

37579

Antigen Source

Human

Images

WB (1:1000)

The anti-PRKAG1 Pab (Cat. #102-27146) is used in Western blot to detect PRKAG1 in mouse heart tissue lysate.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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