Anti-ANAPC11 (C-term) Antibody

Product Description

Specifications

Size	200 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9NYG5\|Q3ZCF6\|Q9CPX9\|Q5R8A2
Gene Id	51529
Gene Symbols	ANAPC11
Protein Name / Synonyms	Anaphase-promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma-associated RING finger protein, ANAPC11
Clonality	Polyclonal
Clone	RB56253
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

Other Information

Antigen Type

Synthesized Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

9841

Antigen Source

Human

Images

WB (1:2000)

All lanes : Anti-ANAPC11 Antibody (C-Term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: PC-3 whole cell lysate Lane 3: T47D whole cell lysate Lane 4: U-2OS whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 10 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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