Anti-AP3M1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9Y2T2
Gene Id	26985
Gene Symbols	AP3M1
Protein Name / Synonyms	AP3M1 (C-term)
Clonality	Polyclonal
Preparation	This AP3M1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human AP3M1.
Concentration (lot specific)	0.460 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed.

Specificity

Predicted Reactivity

Mouse, Bovine

Other Names

AP3M1; AP-3 complex subunit mu-1; AP-3 adapter complex mu3A subunit; Adapter-related protein complex 3 mu-1 subunit; Mu-adaptin 3A; Mu3A-adaptin

NCBI Accession #

NP_036227.1;NP_996895.1

Other Accession #

Q9JKC8; Q24K11; NP_036227.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

46939

Recommended Dilutions

WB: 1:1000

AP3M1 Antibody (C-term) (Cat# 102-13622) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the AP3M1 antibody detected the AP3M1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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