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Anti-APCS Antibody

Catalog #: 144-65443

APCS pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
P02743
Gene Id
325
Gene Symbols
APCS
Protein Name / Synonyms
APCS, HEL-S-92n, PTX2, SAP, serum amyloid P-component
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting, IHC
Research AreaInflammation
Shipping TypeBlue ice
Storage-20°C

Description

Background

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:100

Format

Calculated MW
25kDa
Observed MW
30kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human APCS (NP_001630.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.