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Anti-APOBEC3G (CEM15) (C-term) Antibody

Catalog #: 102-12037

Rabbit Anti-Human APOBEC3G (CEM15) (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9HC16
Gene Id
60489
Gene Symbols
APOBEC3G
Protein Name / Synonyms
APOBEC3G (CEM15) (C-term)
ClonalityPolyclonal
PreparationThis APOBEC3G (CEM15) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-384 amino acids from the C-terminal region of human APOBEC3G (CEM15).
Concentration (lot specific)
2.0 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

CEM15 is a member of the cytidine deaminase family. It is the product of one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. CEM15 has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.

Specificity

Other Names
APOBEC3G; DNA dC->dU-editing enzyme APOBEC-3G; APOBEC-related cytidine deaminase; APOBEC-related protein 9; CEM-15; Deoxycytidine deaminase
NCBI Accession #
NP_068594.1

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
46408
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
The anti-CEM15 Pab (Cat# 102-12037) is used in Western blot to detect CEM15 in A375 cell lysate.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.