Anti-ARHGEF11 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O15085
Gene Id	9826
Gene Symbols	ARHGEF11
Protein Name / Synonyms	ARHGEF11 (Center)
Clonality	Polyclonal
Preparation	This ARHGEF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Specificity

Predicted Reactivity

Rat

Other Names

ARHGEF11; KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF

NCBI Accession #

NP_055599.1;NP_937879.1

Other Accession #

Q9ES67; NP_055599.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

167704

Recommended Dilutions

WB: 1:1000

ARHGEF11 Antibody (Center) (Cat# 102-13197) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ARHGEF11 antibody detected the ARHGEF11 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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