Anti-ASCL1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P50553
Gene Id	429
Gene Symbols	ASCL1
Protein Name / Synonyms	ASCL1(N-term)
Clonality	Polyclonal
Preparation	This ASCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human ASCL1.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

Specificity

Other Names

ASCL1; ASH1; BHLHA46; HASH1; Achaete-scute homolog 1; Class A basic helix-loop-helix protein 46

NCBI Accession #

NP_004307.2

Other Accession #

NP_004307.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

25454

Recommended Dilutions

WB: 1:1000

ASCL1 Antibody (N-term) (Cat# 102-14402) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ASCL1 antibody detected the ASCL1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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