Anti-ASGR1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P07306
Gene Id	432
Gene Symbols	ASGR1
Protein Name / Synonyms	ASGR1 (N-term)
Clonality	Polyclonal
Preparation	This ASGR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ASGR1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Specificity

Other Names

ASGR1; CLEC4H1; Asialoglycoprotein receptor 1; C-type lectin domain family 4 member H1; Hepatic lectin H1

NCBI Accession #

NP_001184145.1;NP_001662.1

Other Accession #

NP_001662.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

33186

Recommended Dilutions

WB: 1:1000

ASGR1 Antibody (N-term) (Cat# 102-12863) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ASGR1 antibody detected the ASGR1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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