Anti-ATP6V0C (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P27449
Gene Id	527
Gene Symbols	ATP6V0C
Protein Name / Synonyms	ATP6V0C (C-term)
Clonality	Polyclonal
Preparation	This ATP6V0C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-126 amino acids from the C-terminal region of human ATP6V0C.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

ATP6V0C is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. ATP6V0C encodes the V0 subunit c.

Specificity

Predicted Reactivity

Rat, Bovine, Drosophila, C.Elegans

Other Names

ATP6V0C; ATP6C; ATP6L; ATPL; V-type proton ATPase 16 kDa proteolipid subunit; Vacuolar proton pump 16 kDa proteolipid subunit

NCBI Accession #

NP_001185498.1;NP_001685.1

Other Accession #

P63081; P63082; P23380; P23956; P34546; NP_001685.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

15736

Recommended Dilutions

WB: 1:1000

ATP6V0C Antibody (C-term) (Cat# 102-10662) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ATP6V0C antibody detected the ATP6V0C protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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