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Anti-Bax Antibody, Sodium Azide Free
Catalog #: 188-11374-SAF
Mouse anti-Human Bax Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Does not react with mouse and rat. Other species not tested. |
| Host Species | Mouse |
| Accession Number | Q07812 |
| Gene Id | 581 |
| Gene Symbols | BAX,BCL2L4 |
| Protein Name / Synonyms | Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4) |
| Immunogen | Recombinant full-length human protein was used as the immunogen for the Bax antibody. |
| Isotype | IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | Immunofluorescence: 1-2ug/ml Western blot: 1-2ug/ml Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT (1) Prediluted format: incubate for 30 min at RT (2) |
| Domain / Region / Terminus | Cytoplasmic |
| Research Area | Apoptosis |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
BCL2 associated X protein/Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. [UniProt]
Storage
Store the Bax antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.