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Anti-BAX (N-term) Antibody
Catalog #: 102-11913
Rabbit Anti-Human BAX (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q07812 |
| Gene Id | 581 |
| Gene Symbols | BAX |
| Protein Name / Synonyms | BAX (N-term) |
| Clonality | Polyclonal |
| Preparation | This BAX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human BAX. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Apoptosis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Specificity
Other Names
BAX; BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4
NCBI Accession #
NP_004315.1;NP_620116.1;NP_620118.1;NP_620119.2
Other Accession #
NP_004315.1; NP_620118.1; NP_620119.2; NP_620116.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
21184
Recommended Dilutions
WB: 1:1000
 | BAX Antibody (N-term) (Cat# 102-11913) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the BAX antibody detected the BAX protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.