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Anti-BCAT1 (Center) Antibody

Catalog #: 102-10567

Rabbit Anti-Human BCAT1 (Center) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P54687
Gene Id
586
Gene Symbols
BCAT1
Protein Name / Synonyms
BCAT1 (Center)
ClonalityPolyclonal
PreparationThis BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human BCAT1.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

Specificity

Predicted Reactivity
Mouse, Rat
Other Names
BCAT1; BCT1; ECA39; Branched-chain-amino-acid aminotransferase, cytosolic; Protein ECA39
NCBI Accession #
NP_001171562.1;NP_001171563.1;NP_001171564.1;NP_001171565.1;NP_005495.2
Other Accession #
P54690; P24288; NP_001171563.1; NP_001171562.1; NP_005495.2; NP_001171564.1; NP_001171565.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42966
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
BCAT1 Antibody (Center) (Cat# 102-10567) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the BCAT1 antibody detected the BCAT1 protein (arrow).
BCAT1 Antibody (Center) (Cat# 102-10567) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCAT1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.