Anti-Bcl-2 (BH3 Domain Specific) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P10415
Gene Id	596
Gene Symbols	BCL2
Protein Name / Synonyms	Bcl-2 (BH3 Domain Specific)
Clonality	Polyclonal
Preparation	This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-110 amino acids from human Bcl.
Concentration (lot specific)	2.000 mg/ml
Recommended Applications	Western Blotting, IHC-P, IF
Research Area	Apoptosis, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

BCL2 is integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.

Specificity

Predicted Reactivity

Bovine

Other Names

BCL2; Apoptosis regulator Bcl-2

NCBI Accession #

NP_000624.2

Other Accession #

O02718

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

26266

Recommended Dilutions

IHC: 1:10-50; IF: 1:10-50

	Formalin-fixed and paraffin-embedded human testis tissue reacted with Bcl-2 BH3 Domain Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
	Confocal immunofluorescent analysis of Bcl-2 Antibody (BH3 Domain Specific) (Cat# 102-11837) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products