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Anti-BCL2L11 (Center) Antibody
Catalog #: 102-17914
Rabbit Anti-Human BCL2L11 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O43521 |
| Gene Id | 10018 |
| Gene Symbols | BCL2L11 |
| Protein Name / Synonyms | BCL2L11 (Center) |
| Clonality | Polyclonal |
| Preparation | This BCL2L11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-160 amino acids from the Central region of human BCL2L11. |
| Concentration (lot specific) | 0.390 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Apoptosis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
BCL2L11 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
BCL2L11; BIM; Bcl-2-like protein 11; Bcl2-interacting mediator of cell death
NCBI Accession #
NP_001191035.1;NP_001191036.1;NP_001191037.1;NP_001191038.1;NP_001191039.1;NP_001191040.1;NP_001191041.1;NP_001191042.1;NP_006529.1;NP_619527.1;NP_619528.1;NP_619529.1;NP_619530.1;NP_619531.1;NP_61953
Other Accession #
O88498; O54918
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22171
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | Western blot analysis of BCL2L11 Antibody (Center) (Cat# 102-17914) in K562, HL-60 cell line lysates (35ug/lane). BCL2L11 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human colon carcinoma reacted with BCL2L11 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Flow cytometric analysis of WiDr cells using BCL2L11 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.