Anti-BEAN (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q3B7T3
Gene Id	146227
Gene Symbols	BEAN1
Protein Name / Synonyms	BEAN (N-term)
Clonality	Polyclonal
Preparation	This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human BEAN.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names

BEAN1; Protein BEAN1; Brain-expressed protein associating with Nedd4 homolog

NCBI Accession #

NP_001129578.1;NP_001171491.1;NP_001184154.1

Other Accession #

NP_001129578.1; NP_001171491.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

28626

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	BEAN Antibody (N-term) (Cat# 102-11993) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BEAN antibody detected the BEAN protein (arrow).
	BEAN Antibody (N-term) (Cat# 102-11993)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BEAN Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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