Anti-BECN1 (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	Q14457
Gene Id	8678
Gene Symbols	BECN1
Protein Name / Synonyms	BECN1 (Ascites)
Clonality	Monoclonal
Preparation	This BECN1 Monoclonal antibody was raised using purified His-tagged recombinant full length human Autophagy BECN1.
Recommended Applications	Western Blotting, IHC-P, IF
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).

Specificity

Other Names

BECN1; GT197; Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197

NCBI Accession #

NP_003757.1

Format

Type

Purified Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

51896

Recommended Dilutions

WB: 1:100-400; IHC: 1:50-100; IF: 1:10-50

	Western blot analysis of anti-BECN1 Monoclonal Antibody (Cat# 102-10047) in Jurkat cell line lysates (35ug/lane). BECN1 (arrow) was detected using the Mab ascites (1:100 dilution).
	Formalin-fixed and paraffin-embedded human brain with BECN1 Monoclonal Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
	Immunofluorescence analysis of BECN1 Monoclonal Antibody with paraffin-embedded human brain tissue .0.05 mg/ml primary antibody was followed by PE-conjugated goat anti-mouse lgG (whole molecule). PE emits orange fluorescence.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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