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Anti-Beta Catenin Antibody
Catalog #: 188-11024
Mouse anti-Human/Cow/Dog/Chicken Beta Catenin Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P35222 |
| Gene Id | 1499 |
| Gene Symbols | CTNNB1,CTNNB,OK,SW-CL.35,PRO2286 |
| Protein Name / Synonyms | Catenin beta-1 (Beta-catenin) |
| Immunogen | Chicken beta-Catenin was used as the immunogen for the b-Catenin antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Flow Cytometry: 0.5-1ug/million cells in 0.1ml Immunofluorescence: 1-2ug/ml Western Blotting: 0.5-1ug/ml IHC (FFPE): 1-2ug/ml |
| Domain / Region / Terminus | Cell surface, cytoplasmic, cell junctions |
| Research Area | Angiogenesis, Cardiovascular Disease, Cancer, Wnt-beta-Catenin Signaling |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Beta Catenin is a dual function protein, regulating the coordination of cellcell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. b-Catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to gamma-Catenin, also known as plakoglobin. b-Catenin is widely expressed in many tissues. In cardiac muscle, it localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte. [Wiki]
Storage
Store the b-Catenin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.