BGLAP pAb
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P02818 |
| Gene Id | 632 |
| Gene Symbols | BGLAP |
| Protein Name / Synonyms | BGLAP, BGP, OC, OCN, osteocalcin |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | IHC, IF |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Dilutions
IHC 1:50 - 1:200; IF 1:50 - 1:200
Format
Calculated MW
10kDa
Observed MW
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BGLAP (NP_954642.1).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.