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Anti-BSCL2 Antibody
Catalog #: 144-63356
BSCL2 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q96G97 |
| Gene Id | 26580 |
| Gene Symbols | BSCL2 |
| Protein Name / Synonyms | BSCL2, GNG3LG, HMN5, PELD, SPG17, seipin |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
32kDa/44kDa/51kDa
Observed MW
46kDa
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human BSCL2 (NP_116056.3).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.