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Anti-Cadherin 16 Antibody
Catalog #: 188-11486-IHC
Rabbit anti-Human/Mouse/Rat Recombinant Cadherin 16 Antibody [IHC only]
Product Description
Specifications
| Size | 7 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Specificity | Other species not tested. |
| Host Species | Rabbit |
| Accession Number | O75309 |
| Gene Id | 1014 |
| Gene Symbols | CDH16,UNQ695,PRO1340 |
| Protein Name / Synonyms | Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin) |
| Immunogen | Human protein was used as the immunogen for the recombinant Cadherin 16 antibody. |
| Isotype | IgG, Kappa |
| Purity | Protein A affinity chromatography |
| Concentration (lot specific) | Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only* |
| Recommended Applications | Prediluted IHC only format: incubate for 30 min at RT (1) |
| Domain / Region / Terminus | Cell surface with some cytoplasmic |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Storage
Store the recombinant Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.