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Anti-Calgranulin A + B Antibody, Sodium Azide Free
Catalog #: 188-10672-SAF
Mouse anti-Human Calgranulin A + B Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P06702 |
| Gene Id | 6280 |
| Gene Symbols | S100A9,CAGB,CFAG,MRP14 |
| Protein Name / Synonyms | Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9) |
| Immunogen | Recombinant human protein was used as the immunogen for the Calgranulin A + B antibody. |
| Isotype | Kappa, IgM |
| Purity | PEG precipitation |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | Flow Cytometry: 0.5-1ug/million cells in 0.1ml Immunofluorescence: 0.5-1ug/ml Immunohistochemistry (Formalin-fixed. Not suitable for frozen tissues.): 0.5-1ug/ml for 30 min at RT (1) |
| Domain / Region / Terminus | Cytoplasmic |
| Research Area | Inflammation, Autophagy |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Recognizes a 12-14kDa doublet of Calgranulin A/B (also known as S100A8/A9 or MRP-8/14); expressed by granulocytes, monocytes and by tissue macrophages. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This mAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
Storage
Store the Calgranulin A + B antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.