Anti-CCBL1 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q16773
Gene Id	883
Gene Symbols	CCBL1
Protein Name / Synonyms	KYAT1, CCBL1, GTK, KAT1, KATI, kynurenine aminotransferase 1
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IHC, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:10 - 1:100

Format

Calculated MW

27kDa/42kDa/47kDa

Observed MW

48kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCBL1 (NP_001116144.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using CCBL1 Antibody (144-06542) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Western blot - CCBL1 Polyclonal Antibody (144-06542)

Immunohistochemistry of paraffin-embedded mouse liver using CCBL1 antibody (144-06542) at dilution of 1:100 (40x lens).
Immunohistochemistry - CCBL1 Polyclonal Antibody (144-06542)

Immunohistochemistry of paraffin-embedded mouse heart using CCBL1 antibody (144-06542) at dilution of 1:100 (40x lens).
Immunohistochemistry - CCBL1 Polyclonal Antibody (144-06542)

Immunofluorescence analysis of U2OS cells using CCBL1 antibody (144-06542). Blue: DAPI for nuclear staining.
Immunofluorescence - CCBL1 Polyclonal Antibody (144-06542)

Expiration:

12 months from the date of shipment when stored properly.

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