Anti-CCR10 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P46092
Gene Id	2826
Gene Symbols	CCR10
Protein Name / Synonyms	CCR10 (N-term)
Clonality	Polyclonal
Preparation	This CCR10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCR10.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	Western Blotting
Research Area	Inflammation, Chemokine Biology
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).

Specificity

Other Names

CCR10; GPR2; C-C chemokine receptor type 10; G-protein coupled receptor 2

NCBI Accession #

NP_057686.2

Other Accession #

NP_057686.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

38416

Recommended Dilutions

WB: 1:1000

CCR10 Antibody (N-term) (Cat# 102-12133) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CCR10 antibody detected the CCR10 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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