3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-CCR8 (C-term) Antibody
Catalog #: 102-10669
Rabbit Anti-Human CCR8 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P51685 |
| Gene Id | 1237 |
| Gene Symbols | CCR8 |
| Protein Name / Synonyms | CCR8 (C-term) |
| Clonality | Polyclonal |
| Preparation | This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CCR8. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Inflammation, Chemokine Biology |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
Specificity
Other Names
CCR8; CKRL1; CMKBR8; CMKBRL2; C-C chemokine receptor type 8; CC chemokine receptor CHEMR1; Chemokine receptor-like 1; GPR-CY6; TER1; CD_antigen=CDw198
NCBI Accession #
NP_005192.1
Other Accession #
NP_005192.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
40844
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | CCR8 Antibody (C-term) (Cat# 102-10669) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CCR8 antibody detected the CCR8 protein (arrow). |
 | CCR8 Antibody (C-term) (Cat# 102-10669) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.