Anti-CCT4 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P50991
Gene Id	10575
Gene Symbols	CCT4
Protein Name / Synonyms	CCT4 (N-term)
Clonality	Polyclonal
Preparation	This CCT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human CCT4.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).

Specificity

Predicted Reactivity

Rat

Other Names

CCT4; CCTD; SRB; T-complex protein 1 subunit delta; CCT-delta; Stimulator of TAR RNA-binding

NCBI Accession #

NP_001243650.1;NP_006421.2

Other Accession #

Q7TPB1; NP_006421.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

57924

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	CCT4 Antibody (N-term) (Cat# 102-12714) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CCT4 antibody detected the CCT4 protein (arrow).
	CCT4 Antibody (N-term) (102-12714)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCT4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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