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Anti-CD14 Antibody (Macrophage Marker), Sodium Azide Free
Catalog #: 188-10288-SAF
Mouse anti-Human CD14 Antibody (Macrophage Marker) [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P08571 |
| Gene Id | 929 |
| Gene Symbols | CD14 |
| Protein Name / Synonyms | Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form] |
| Immunogen | Human CD14/LPSR recombinant protein was used as immunogen for this CD14 antibody. |
| Isotype | Kappa, IgG2b |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS (pH 7.4), BSA free, sodium azide free |
| Recommended Applications | Flow Cytometry: 0.5-1ug/million cells Immunofluorescence: 0.5-1ug/ml,, |
| Domain / Region / Terminus | Cell surface |
| Research Area | Cancer, Inflammation, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Recognizes a protein of 55kDa, identified as Cluster of Differentiation 14 (also known lipopolysaccharide receptor or LPSR). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. It is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.
Storage
CD14 antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Expiration:
12 months from the date of shipment when stored properly.