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Anti-CD147 Antibody
Catalog #: 188-10012
Mouse anti-Human CD147 Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P35613 |
| Gene Id | 682 |
| Gene Symbols | BSG,UNQ6505,PRO21383 |
| Protein Name / Synonyms | Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147) |
| Immunogen | Human T cell line Molt-13 was used as the immunogen for this CD147 antibody. |
| Isotype | IgG1 |
| Purity | Protein G purified CD147 antibody |
| Concentration (lot specific) | 0.2 mg/ml in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Functional Activity: Inhibits homotypic aggregation and adhesion to matrix proteins: order BSA-free antibody format FACS: 0.5-1ug/million cells IF: 1:100-1:200 IHC (FFPE): 1-2ug/ml for 30 minutes at RT (1) Prediluted format: incubate for 30 min at RT (2) |
| Domain / Region / Terminus | Cell surface, cytoplasmic |
| Research Area | Angiogenesis, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
Storage
Store the CD147 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.