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Anti-CD27 Antibody
Catalog #: 144-63859
CD27 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | P26842 |
| Gene Id | 939 |
| Gene Symbols | CD27 |
| Protein Name / Synonyms | CD27, S152, S152. LPFS2, T14, TNFRSF7, Tp55, S152.LPFS2, CD27 antigen |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Inflammation, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
29kDa
Observed MW
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-191 of human CD27 (NP_001233.1).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Expiration:
12 months from the date of shipment when stored properly.