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Anti-CD3e Antibody, Sodium Azide Free
Catalog #: 188-10024-SAF
Rabbit anti-Human/Mouse/Rat/Primate/Guinea Pig/Hamster/Horse/Mole Rat/Pig/Rabbit/Sheep/Cat/Chicken/Cow/Dog/Frog/Opossum/Elephant CD3e Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P07766 |
| Gene Id | 916 |
| Gene Symbols | CD3E,T3E |
| Protein Name / Synonyms | T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e) |
| Immunogen | Amino acids ERPPPVPNPDYEP (156-168) were used as the immunogen for this CD3e antibody. |
| Isotype | IgG |
| Purity | Protein A purified CD3e antibody |
| Concentration (lot specific) | 1 mg/ml in 1X PBS (pH 7.4), BSA free, sodium azide free |
| Recommended Applications | FACS: use the CD3e antibody at 0.5-1ug/million cells Western Blotting: 0.5-1.0ug/ml IP: 1-2ug/500ug protein lysate, |
| Domain / Region / Terminus | Cell surface and cytoplasmic |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.
Storage
Store the CD3e antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.