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Anti-CD3E (C-term) Antibody
Catalog #: 102-12040
Rabbit Anti-Human CD3E (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P07766 |
| Gene Id | 916 |
| Gene Symbols | CD3E |
| Protein Name / Synonyms | CD3E (C-term) |
| Clonality | Polyclonal |
| Preparation | This CD3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human CD3E. |
| Concentration (lot specific) | 0.350 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Specificity
Predicted Reactivity
Monkey
Other Names
CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen=CD3e; Flags: Precursor
NCBI Accession #
NP_000724.1
Other Accession #
Q95LI5; NP_000724.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23147
Recommended Dilutions
WB: 1:1000
 | CD3E Antibody (C-term) (Cat# 102-12040) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CD3E antibody detected the CD3E protein (arrow). |
 | Western blot analysis of CD3E (arrow) using rabbit polyclonal CD3E Antibody (C-term) (Cat# 102-12040). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD3E gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.