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Anti-CD3G (N-term) Antibody
Catalog #: 102-12743
Rabbit Anti-Human CD3G (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P09693 |
| Gene Id | 917 |
| Gene Symbols | CD3G |
| Protein Name / Synonyms | CD3G (N-term) |
| Clonality | Polyclonal |
| Preparation | This CD3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human CD3G. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Autoimmune Disease, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in the CD3G gene are associated with T cell immunodeficiency.
Specificity
Other Names
CD3G; T3G; T-cell surface glycoprotein CD3 gamma chain; T-cell receptor T3 gamma chain; CD_antigen=CD3g; Flags: Precursor
NCBI Accession #
NP_000064.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
20469
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | CD3G Antibody (N-term) (Cat# 102-12743) western blot analysis in RPMI8226 cell line lysates (35ug/lane).This demonstrates the CD3G antibody detected the CD3G protein (arrow). |
 | Formalin-fixed and paraffin-embedded human brain tissue reacted with CD3G antibody (N-term) (Cat# 102-12743), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Flow cytometric analysis of HL-60 cells using CD3G Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.