Anti-CD3Z (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P20963
Gene Id	919
Gene Symbols	CD247
Protein Name / Synonyms	CD3Z (C-term)
Clonality	Polyclonal
Preparation	This CD3Z antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the C-terminal region of human CD3Z.
Concentration (lot specific)	0.470 mg/ml
Recommended Applications	FC, Western Blotting
Research Area	Adaptive Immunity
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

T-cell receptor zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response.

Specificity

Predicted Reactivity

Pig

Other Names

CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD_antigen=CD247; Flags: Precursor

NCBI Accession #

NP_000725.1;NP_932170.1

Other Accession #

Q9XSJ9

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

18696

Recommended Dilutions

WB: 1:1000

Western blot analysis of CD3Z (arrow) using rabbit polyclonal CD3Z Antibody (C-term) (Cat#1413b).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CD3Z gene (Lane 2) (Origene Technologies).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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