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Anti-CD45RB Antibody, PE
Catalog #: 188-10166-PE
Mouse anti-Human CD45RB Antibody [PE Conjugated]
Product Description
Specifications
| Size | 100 tests |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Does not react with rat and rhesus monkey. Other species not tested. |
| Host Species | Mouse |
| Accession Number | P08575 |
| Gene Id | 5788 |
| Gene Symbols | PTPRC,CD45 |
| Protein Name / Synonyms | Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) |
| Immunogen | The non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V) was used as the immunogen for this antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 500 ul at 0.1 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Flow Cytometry: 5ul/test/10e6 cells in 100ul (or 5ul per 100ul of whole blood) Immunofluorescence: 1:50-1:100 |
| Domain / Region / Terminus | Cell surface and cytoplasmic |
| Research Area | Cancer, Inflammation, Autoimmune Disease, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | 2-8°C |
Description
Description
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. antibody to CD45R is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Storage
Store the CD45RB antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Expiration:
12 months from the date of shipment when stored properly.