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Anti-CD68 Antibody
Catalog #: 188-10960
Mouse anti-Human CD68 Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Does not react with rat. Other species not tested. |
| Host Species | Mouse |
| Accession Number | P34810 |
| Gene Id | 968 |
| Gene Symbols | CD68 |
| Protein Name / Synonyms | Macrosialin (Gp110) (CD antigen CD68) |
| Immunogen | The subcellular fraction of human alveolar macrophages was used as the immunogen for this CD68 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Immunohistochemistry (FFPE) : 1-2 µg/ml for 30 min at RT |
| Domain / Region / Terminus | Cytoplasmic, membrane |
| Research Area | Inflammation, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Storage/Stability
Store the CD68 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration
12 months from the date of shipment when stored properly.
Description
This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.