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Anti-CD68 Antibody Cocktail

Catalog #: 188-10048-IHC

Mouse anti-Human/Monkey/Mouse/Rat/Cat CD68 Antibody Cocktail [IHC only]

Product Description

Specifications

Size7 mL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat, Feline (cat)
Specificity
Other species not known
Host SpeciesMouse
Accession Number
P34810
Gene Id
968
Gene Symbols
CD68
Protein Name / Synonyms
Macrosialin (Gp110) (CD antigen CD68)
Immunogen
The subcellular fraction of human alveolar macrophages was used as the immunogen for this CD68 antibody.
IsotypeKappa, IgG1
Purity
Protein G affinity chromatography
Concentration (lot specific)
Prediluted in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*
Recommended ApplicationsPrediluted format : incubate for 30 min at RT (2)
Domain / Region / TerminusCytoplasmic, membrane
Research AreaInflammation, Adaptive Immunity
Shipping TypeBlue ice
Storage≤-20°C

Description

Description

This antibody cocktail recognizes a glycoprotein of 110kDa, which is identified as CD68. antibody to CD68 is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. CD68 antibody reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. CD68 shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

Storage

Store the CD68 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.