Anti-CD73 (NT5E) (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P21589
Gene Id	4907
Gene Symbols	NT5E
Protein Name / Synonyms	5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase, CD73, NT5E, NT5, NTE
Clonality	Polyclonal
Clone	RB02844
Isotype	Kappa, Rabbit
Recommended Applications	IHC-P
Research Area	Inflammation, Adaptive Immunity
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Ecto-5-prime-nucleotidase catalyzes conversion at neutral pH of purine 5-prime mononucleotides to nucleosides. The enzyme consists of a dimer of 2 identical 70 kD subunits tethered by a glycosyl phosphatidyl inositol moeity to the exterior plasma membrane surface. The enzyme, a marker of lymphocyte differentiation is associated in deficiency with a variety of immunodeficiency diseases. The preferred substrate is AMP. The NT5 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations.

Other Information

NCBI Accession #

NP_001191742.1;NP_002517.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Calculated Molecular Weight (Da)

63368

Antigen Source

Human

Images

IHC-P (1:10~50)

CD73 (NT5E) Antibody (N-term) (Cat. #102-23789)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD73 (NT5E) Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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