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ISO 13485:2016 cGMP
Anti-CD86 Antibody
Catalog #: DS-MB-03224
Mouse Anti-Human CD86 (25 ug)
Product Description
Specifications
| Size | 25 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Mouse anti Human CD86 antibody recognizes human CD86 also known as B7-2, a type I transmembrane protein expressed by monocytes and activated B cells. CD86 acts as a co - stimulaory molecule along with CD80 and is a ligand for CD28 and CTLA-4. CD86 is a member of the Immunoglobulin superfamily and carries an extracellular domain bearing both an Ig -v -like domain which contains the CTLA -4 binding site and an adjacent C2-like domain. CD86 plays an important role in co - stimulation of T cell proliferation , IL-2 production and in the primary immune response. Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, clone Bu63 is located within the Ig -v -like domain of human CD86. Studies suggest that CD86 along with CD80 may be exploited as receptors for adenovirus entry into cells. |
| Host Species | Mouse |
| Protein Name / Synonyms | CD86 |
| Concentration (lot specific) | IgG concentration 1.0 mg/ml |
| Recommended Applications | Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
TRIS buffered saline
Format Type:
Purified
Preparation
Immunogen:
Human peripheral blood lymphocytes.
Preservative:
| 0.09% | Sodium Azide |
This product
Spleen cells from immunised mice were fused with cells of the P3 X63 Ag8.653 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.