Anti-CD8B1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P10966
Gene Id	926
Gene Symbols	CD8B
Protein Name / Synonyms	CD8B1 (C-term)
Clonality	Polyclonal
Preparation	This CD8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-167 amino acids from the C-terminal region of human CD8B1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Adaptive Immunity
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Specificity

Other Names

CD8B; CD8B1; T-cell surface glycoprotein CD8 beta chain; CD_antigen=CD8b; Flags: Precursor

NCBI Accession #

NP_001171571.1;NP_004922.1;NP_742099.1;NP_742100.1;NP_757362.1

Other Accession #

A6NJW9; NP_004922

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

23722

Recommended Dilutions

WB: 1:1000

CD8B1 Antibody (C-term) (Cat# 102-11330) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CD8B1 antibody detected the CD8B1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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