Anti-CD97 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P48960
Gene Id	976
Gene Symbols	CD97
Protein Name / Synonyms	CD97 (C-term)
Clonality	Polyclonal
Preparation	This CD97 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 707-736 amino acids from the C-terminal region of human CD97.
Concentration (lot specific)	0.450 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Inflammation, Adaptive Immunity
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene cluster on the short arm of chromosome 19. The encoded product is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. The protein has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation. Alternative splicing has been observed for this gene and three variants have been found.

Specificity

Other Names

CD97; CD97 antigen; Leukocyte antigen CD97; CD_antigen=CD97; CD97 antigen subunit alpha; CD97 antigen subunit beta

NCBI Accession #

NP_001020331.1;NP_001775.2;NP_510966.1

Other Accession #

NP_001775.2; NP_510966.1; NP_001020331.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

91869

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	CD97 Antibody (C-term) (Cat# 102-12150) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CD97 antibody detected the CD97 protein (arrow).
	CD97 Antibody (C-term) (Cat# 102-12150)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD97 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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