Anti-CDC73 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q6P1J9\|Q4V8C8\|Q8JZM7\|Q5ZLM0
Gene Id	79577
Gene Symbols	CDC73
Protein Name / Synonyms	Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein, CDC73, C1orf28, HRPT2
Clonality	Polyclonal
Clone	RB23239
Isotype	Kappa, Rabbit
Recommended Applications	FC, IHC-P, Western Blotting, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin.

Other Information

NCBI Accession #

NP_078805.3

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

60577

Antigen Source

Human

Images

FC (1:25)

Overlay histogram showing U-2OS cells stained with 102-27676 (green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (102-27676, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(OH191631) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG (1?g/1x10

Expiration:

12 months from the date of shipment when stored properly.

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