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Anti-CFTR Antibody
Catalog #: 188-11033
Mouse anti-Human/Mouse CFTR Antibody / Cystic Fibrosis Transmembrane Regulator
Product Description
Specifications
| Size | 20 µg, 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P13569 |
| Gene Id | 1080 |
| Gene Symbols | CFTR,ABCC7 |
| Protein Name / Synonyms | Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 3.6.3.49) (cAMP-dependent chloride channel) |
| Immunogen | Human partial recombinant protein was used as the immunogen for this CFTR antibody. |
| Isotype | IgG2a |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | IF: 0.5-1ug/ml Western blot: 0.5-1ug/ml IHC (FFPE): 0.5-1ug/ml for 30 min at RT |
| Domain / Region / Terminus | Cell surface, cytoplasmic |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
Storage
Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.