Anti-CIDEA (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O60543
Gene Id	1149
Gene Symbols	CIDEA
Protein Name / Synonyms	CIDEA (C-term)
Clonality	Polyclonal
Preparation	This CIDEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human CIDEA.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Apoptosis, Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Specificity

Other Names

CIDEA; Cell death activator CIDE-A; Cell death-inducing DFFA-like effector A

NCBI Accession #

NP_001270.1

Other Accession #

NP_001270.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

24687

Recommended Dilutions

WB: 1:1000

CIDEA Antibody (C-term) (Cat# 102-12285) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CIDEA antibody detected the CIDEA protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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