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Anti-Claudin 1 (CLDN1) (Loop2) Antibody
Catalog #: 102-16740
Rabbit Anti-Claudin 1 (CLDN1) (Loop2) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | O95832 |
| Gene Id | 9076 |
| Gene Symbols | CLDN1 |
| Protein Name / Synonyms | Claudin 1 (CLDN1) (Loop2) |
| Clonality | Polyclonal |
| Preparation | This Claudin 1(CLDN1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-163 amino acids from human Claudin 1(CLDN1). |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Specificity
Predicted Reactivity
Rat, Bovine
Other Names
CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein
NCBI Accession #
NP_066924.1
Other Accession #
P56745; Q6L708
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22744
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-hCLDN1-Loop2 Pab (Cat# 102-16740) in mouse kidney tissue lysates (35ug/lane). CLDN1(arrow) was detected using the purified Pab. |
 | Western blot analysis of CLDN1 (arrow) using rabbit polyclonal CLDN1 Antibody (Loop2) (Cat# 102-16740). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLDN1 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.