Anti-COG2 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q14746
Gene Id	22796
Gene Symbols	COG2
Protein Name / Synonyms	COG2, LDLC, CDG2Q, component of oligomeric golgi complex 2
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IHC
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Format

Calculated MW

83kDa

Observed MW

88kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human COG2 (NP_031383.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using COG2 antibody (144-06251) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 15s.
Western blot - COG2 antibody (144-06251)

Immunohistochemistry of paraffin-embedded rat brain using COG2 antibody (144-06251) at dilution of 1:100 (40x lens).
Immunohistochemistry - COG2 antibody (144-06251)

Immunohistochemistry of paraffin-embedded mouse kidney using COG2 antibody (144-06251) at dilution of 1:100 (40x lens).
Immunohistochemistry - COG2 antibody (144-06251)

Expiration:

12 months from the date of shipment when stored properly.

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