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Anti-CPSF3L (N-term) Antibody

Catalog #: 102-10974

Rabbit Anti-Human CPSF3L (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q5TA45
Gene Id
54973
Gene Symbols
CPSF3L
Protein Name / Synonyms
CPSF3L (N-term)
ClonalityPolyclonal
PreparationThis CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human CPSF3L.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P, IF
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).

Specificity

Predicted Reactivity
Mouse, Rat, Bovine
Other Names
CPSF3L; INTS11; RC68; Integrator complex subunit 11; Cleavage and polyadenylation-specific factor 3-like protein; Protein related to CPSF subunits of 68 kDa
NCBI Accession #
NP_001243385.1;NP_001243389.1;NP_001243391.1;NP_001243392.1;NP_060341.2
Other Accession #
Q3MHC2; Q9CWS4; Q2YDM2; NP_060341.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
67663
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50
CPSF3L Antibody (N-term) (Cat# 102-10974) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CPSF3L antibody detected the CPSF3L protein (arrow).
CPSF3L Antibody (N-term) (Cat# 102-10974)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CPSF3L Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of CPSF3L Antibody (N-term)(Cat# 102-10974) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.