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Anti-CREM Antibody
Catalog #: 144-65951
CREM pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q03060 |
| Gene Id | 1390 |
| Gene Symbols | CREM |
| Protein Name / Synonyms | CREM, CREM-2, ICER, hCREM-2, cAMP-responsive element modulator |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
Dilutions
WB 1:500 - 1:2000; IHC 1:50 - 1:200
Format
Calculated MW
11-38kDa
Observed MW
39kDa
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CREM (NP_853549.1).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.